英语翻译Thereadilyavailablestartingmaterial1waspreparedinourpreviouscontributions.10SixhexylgroupswereattachedtotheC-5,C-10,andC-15positionsofthetruxenemoietytoincreasesolubilityaswellastoreleaseintermolecularπ-π|小学英语问答-字典翻译问答网

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英语翻译Thereadilyavailablestartingmaterial1waspreparedinourpreviouscontributions.10SixhexylgroupswereattachedtotheC-5,C-10,andC-15positionsofthetruxenemoietytoincreasesolubilityaswellastoreleaseintermolecularπ-π

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英语翻译

Thereadilyavailablestartingmaterial1waspreparedin

ourpreviouscontributions.10Sixhexylgroupswereattached

totheC-5,C-10,andC-15positionsofthetruxenemoiety

toincreasesolubilityaswellastoreleaseintermolecularπ-π

stacking.AsshowninScheme1,withacontrolledamount

ofiodineandperiodicacidhydrate,selectiveelectrophilic

iodinationatonebranchofthetruxenesegmentafforded

themonosubstitutedtruxeneiodide2ingoodyield(83%).11

Undernitrogenatmosphere,additionofn-butyllithiumat-78

CfollowedbyadditionofB(OCH3)3,hydrolysisby50%H2SO4aqueoussolution,andesterificationby1,3-propyldiol

generatedester3inmoderateyield(43%).Thestandard

Suzukicouplingreaction12between3and2,7-dibromo-9,9-

spirobifluorene(4)13withPd(PPh3)4ascatalystintoluene

providedthetargetmoleculeTM1efficiently(86%).

TM2waspreparedbyrepetitivepalladium-catalyzed

Sonogashiracouplingreactionfrom2(Scheme2).Acetylenic

alcohol5wasreadilyobtainedviatheSonogashiracoupling

[Pd(PPh3)4,CuI,Et3N]ofiodide2and2-methylbut-3-yn-

2-ol.14Itshouldbenotedthattheutilizationof2-methylbut-

3-yn-2-olinsteadoftrimethylsilylacetylene(TMSA)is

necessarytoobtainpureintermediate,duetotheincreased

polaritydifferencebetweenthestartingmaterialandthe

product.Theone-potSonogashiracouplingbetweenthe

acetylenicalcohol5andaryliodide2tookplaceinatwo-

phaseheterogeneoussysteminthepresenceofaphase-

transferreagentandanaqueousbase.15Underthesecondi-

tions,acetylenealcohol5transformedintothearylethyne

intermediate,whichcoupledwitharyliodide2immediately.

50大洋

冯仪回答：

　　可用的原材料1准备了　　our早先contributions.10六己基的小组附上　　totruxene份额的C-5、C-10和C-15位置　　to并且发布分子间的π-π的增量可溶性　　stacking.如与受控数额的计划1所显示, 　　of碘和高碘酸含水物,有选择性亲电子在truxene段的一个分支的iodination买得起在好出产量(83%).11的themonosubstitutedtruxene碘化物2 　　Under氮气大气,n-butyllithium的加法在-78的　　C被B跟随了(OCH3)3,加水分解根据50%H2SO4aqueous解答和酯化的加法被1,3-propyldiol在适度出产量(43%)的generated酯类3.标准在3和2,7-dibromo-9,9-之间的Suzuki联结reaction12 　　spirobifluorene(4)13with在甲苯的Pd(PPh3)4as催化剂　　provided目标分子高效率TM1(86%). 　　TM2由钯摧化的反复准备　　Sonogashira从2的偶联反应(计划2).与乙炔相象　　alcohol5通过Sonogashira联结欣然获得了　　[Pd(PPh3)4,CuI,Et3N]碘化物2和2-methylbut-3-yn-的2-ol.14It2-methylbut-的运用应该注意而不是trimethylsilylacetylene(TMSA)的3-yn-2-ol是得到纯净的中间体的necessary,由于增加的原材料之间的polarity区别和　　product.在之间的一罐Sonogashira联结　　acetylenic酒精5和芳香族羟基的碘化物2在一二发生了在阶段面前的phase异种系统　　transfer试剂和在这些之下的含水base.15condi- 　　tions,乙炔酒精5变换了成arylethyne 　　intermediate,立刻加上芳香族羟基的碘化物2.

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